What causes suspicion of amyloidosis?

Symptoms of amyloidosis vary greatly and depend on which tissue and organs are affected, and to what degree, meaning, how much amyloid is accumulated. The symptoms can be anything from light and rather diffuse to severe and associated with poor function of one or more organs.

Fatigue, reduced work ability, weight loss and dizziness are frequent, common, but uncharacteristic symptoms.

Other symptoms are characteristic in their effect on the organs:

Heart: Shortness of breath, swollen legs (edema)
Kidney: Foaming urine; swollen legs and general water retention.
Skin: Spontaneous hemorrhaging of the skin, frequently around the eyes. Tingly feeling in the hands (Carpal tunnel syndrome). Soft lump formation.
Intestines: Loose stool/diarrhea
Tongue: Tongue growth
Lungs: Shortness of breath